6-carboxi tetrahidropterina sintasa

Plantía:Ficha de proteína La 6-carboxi tetrahidropterina sintasa o CPH4 sintasa (EC 4.1.2.50) ye una enzima col nome sistémico 7,8-dihidroneopterina 3'-trifosfata de acetaldehído-liasa (6-carboxi-5,6,7,8-tetrahidropterina + trifosfata) ^[1]^[2] Esta enzima cataliza la siguiente reacción química: 7,8-dihidroneopterina 3'-trifosfato + H2O $\rightleftharpoons$ 6-carboxi-5,6,7,8-tetrahidropterina + acetaldehído + trifosfato Esta enzima xúnese Zn2 +. MDMA o 3,4-metilendioximetanfetamina

7,8-dihidroneopterina 3'-trifosfato + H₂O

\rightleftharpoons

6-carboxi-5,6,7,8-tetrahidropterino + acetaldehído + trifosfato

Referencies[editar | editar la fonte]

↑ Cicmil, N. and Shi, L. (2008). «Crystallization and preliminary X-ray characterization of queD from Bacillus subtilis, an enzyme involved in queuosine biosynthesis». Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun. 64: páxs. 119-122. doi:10.1107/s1744309108000924. PMID 18259064.
↑ McCarty, R.M., Somogyi, A. and Bandarian, V. (2009). «Escherichia coli QueD is a 6-carboxy-5,6,7,8-tetrahydropterin synthase». Biochemistry 48: páxs. 2301-2303. doi:10.1021/bi9001437. PMID 19231875.

[1] Cicmil, N. and Shi, L. (2008). «Crystallization and preliminary X-ray characterization of queD from Bacillus subtilis, an enzyme involved in queuosine biosynthesis». Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun. 64: páxs. 119-122. doi:10.1107/s1744309108000924. PMID 18259064.

[2] McCarty, R.M., Somogyi, A. and Bandarian, V. (2009). «Escherichia coli QueD is a 6-carboxy-5,6,7,8-tetrahydropterin synthase». Biochemistry 48: páxs. 2301-2303. doi:10.1021/bi9001437. PMID 19231875.

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